The Gila monster is named after the Gila River in Arizona and is the most venomous lizard native to the U.S. The Gila monster eats large meals infrequently, with a fat reserve stored in its tail, and can consume a meal of one-third of its body weight. They are immune to their own venom — when two males decide to fight over a female, the venom from their bites won’t kill their opponent.